Surgery offers the only hope of slowing or stopping the slow, progressive destruction of the joint that invariably occurs. (2ndchance.info)
Lymphocytic thyroiditis, probably immune - mediated, is characterized histologically by a diffuse infiltration of the gland by lymphocytes, plasma cells, and macrophages and results in progressive destruction of follicles and secondary fibrosis. (merckvetmanual.com)
Summary: Glaucoma is a leading cause of irreversible blindness worldwide and is characterized by progressive destruction of neural connections between retinal ganglion cells and the brain. (glaucoma.org)