We have a large pipeline of promising drug candidates fueled by a bold vision to one day cure cancer. (sciencemag.org)
Even with promising drug candidates, there are often studies that show negative effects, for instance if the dose was too low or the timing of the drug's administration wasn't ideal. (sciencemag.org)
Worse, many promising drug candidates fail in phase II clinical trials when their efficacy is put to the test. (scientificamerican.com)