A healthy cell possesses a whole series of such protective genes to prevent cancer from developing. (sciencedaily.com)
But he points out that supercentenarians (those living past age 110) share even more genetic factors than centenarians, possibly improving the chances of finding protective gene variants. (scientificamerican.com)
To counteract the potential damage arising from ROS, excitotoxicity and other dangers, animals including humans have evolved sophisticated physiological defenses such as the Nrf2 pathway, a molecular network that triggers the expression of a suite of protective genes when cellular function is under threat. (sciencedaily.com)