«Protective mutations like the one we've just identified for heart disease are a treasure trove for understanding human biology,» said senior author Sekar Kathiresan, MD, of the Broad Institute, and director of preventive cardiology at Massachusetts General Hospital. (sciencedaily.com)
The existence of this natural protective mutation was first reported in Nature in 1996. (discovermagazine.com)
«Defining the biology of naturally occurring protective mutations is quite important, because they define desired outcomes for potentially new therapies,» explained the study's co-author Judy H. Cho, MD, Director of the Sanford Grossman Center for Integrative Studies in Crohn's disease, and the Charles F. Bronfman Institute for Personalized Medicine at the Icahn School of Medicine at Mount Sinai. (sciencedaily.com)