"Protein homeostasis" refers to the balance or equilibrium of proteins in a living organism's cells. It involves maintaining the right amount, shape, and function of proteins to ensure proper cellular functioning and overall health. Full definition
She further uses global analysis of protein turnover to characterize changes in protein homeostasis in long - lived fly strains. (buckinstitute.org)
The broad conservation of neurohormonal signaling pathways between mammalian systems and C. elegans such as insulin - like signaling, serotonin, etc., validates studying the cell non-autonomous control of protein homeostasis by the nervous system of C. elegans to instruct our understanding of age - related human disease. (ellisonfoundation.org)
Some of Gierasch's more recent work has been focused on developing and testing experimentally a computational model of cellular protein homeostasis in E. coli in collaboration with Evan Powers of The Scripps Institute. (asbmb.org)