The broad applicability of the GAIM mechanism allows the Company to target a large number of protein misfolding diseases, including neurodegenerative and peripheral diseases. (proclarabio.com)
Products from an early stage of fibril formation were even more toxic to cells than the final, fibrillar form — just as some researchers suspect is the case for early stages of protein misfolding in Alzheimer's disease. (sciencemag.org)
Rates of dementia, specifically Alzheimer's Disease, an autoimmune disease characterized by protein misfolding in the brain, are rising. (dietselfhelp.com)