In the study that's grabbed headlines recently, Mallucci's team went fishing for drugs that could reduce the unfolded protein response in neurons, without poisoning other organs. (en.hdbuzz.net)
«These discoveries demonstrate a hypothesis that we had made following a basic research study we had just carried out in our laboratory, and thus confirm the physiological importance of the unfolded protein response in the control of neurogenesis,» says Laurent Nguyen. (sciencedaily.com)
This thesis primarily investigates the effects of mechanical cyclic stretching, a 5 % low oxygen atmosphere and the Rho - kinase inhibitor, Y - 27632, on protein responses in chondrocytic human chondrosarcoma (HCS - 2 / 8) cells. (umu.diva-portal.org)