Objective: Shame has long been seen as relevant to substance use disorders, but interventions have not been tested in randomized trials. (contextualscience.org)
The finding, which stems from the largest randomized trial in cardiac surgery ever conducted, challenges a practice that many surgeons have used for decades. (sciencedaily.com)
Historically, such considerations have made it unnecessary to conduct randomized trials of some interventions for evaluation of clinical event outcomes (47). (academic.oup.com)