Unfortunately, individuals infected by CXCR4 utilizing strains experience a faster rate of disease progression [20, 21]. (thno.org)
Smokers additionally experienced a higher rate of disease progression over an 8 - year cumulative incidence rate, with a rate of 12 % in smokers vs. 7 % in nonsmokers. (cancernetwork.com)
The criteria have not been finalized but, at the moment, we will exclude patients with GBA mutations as they are associated with a faster rate of disease progression. (tmrwedition.com)