The location of various receptor systems in control parameter space dictates their specific function and regulation. (pnnl.gov)
Dr. Chartoff also studies the mechanisms by which kappa - opioid receptor systems modulate cocaine reward and the depressive - like states induced by cocaine withdrawal. (mcleanhospital.org)
Results, which were published in the June 1 issue of PLoS Computational Biology, have implications for how evolutionary pressures can improve the function of receptor systems by selectively optimizing a few fundamental dynamical parameters. (pnnl.gov)