While the authors do note that further tweaks to the process may be required to remedy the relatively low amount of PLPs produced, this still represent an excellent first step towards the clinical applicability of this therapeutically relevant cell type. (stemcellsportal.com)
Overall, this simple technique (see figure for overview) produces therapeutically relevant cells in a safe and efficacious manner, which may be used in in vitro models for the investigation of glaucoma disease mechanisms, RGC development, drug testing, and may in the future lead to a treatment of glaucomatous neuropathy. (stemcellsportal.com)
This talk will review the evidence of oxygen's fundamental role in regulating cell function and discuss new technologies for controlling the cell culture atmosphere in the generation of physiologically relevant cell data. (immunology2018.org)