This genetic manipulation could be adapted to make malaria - resistance mutations more prevalent in mosquito populations. (newscientist.com)
Paweletz and his colleagues are now developing a PCR - based test to detect drug resistance mutations in lung tumors. (sciencemag.org)
The second manuscript entitled, A Highly Sensitive and Quantitative Test Platform for Detection of NSCLC EGFR Mutations in Urine and Plasma, analyzed samples from patients enrolled in TIGER - X, a phase 1/2 clinical study of rociletinib in previously treated patients with EGFR mutant - positive advanced NSCLC, to interrogate EGFR activating mutations and the T790M resistance mutation by analyzing ctDNA from urine or blood plasma. (iaslc.org)