The researchers began their study as a way to explore epigenetics, a process by which organisms modulate their gene expression in response to environmental cues without changing the underlying sequence of their DNA. (sciencedaily.com)
«Our data suggests that, during development, relative brain parts change their size in response to environmental cues without affecting overall brain size: increasing certain parts forces others to decrease concurrently. (sciencedaily.com)
«We provide the first evidence that the PPARα - dependent gene Fgf21 demethylation occurs in the postnatal mouse liver, and once established it persists into adulthood and exerts long - term effects on the magnitude of gene expression response to environmental cues, which may account in part for the attenuation of diet - induced obesity (Figure).» (sciencedaily.com)