«Such physical proximity means that they will always co-segregate during inheritance, which is why we had to do what we did — modify and analyze each variant independently while keeping the rest of the genome completely constant.» (sciencedaily.com)
They then examined patterns of genetic variation and evolutionary change in those regions relative to the rest of the genome at an unprecedented level of detail. (sciencedaily.com)
The effect was to create new variants of the targeted genes while leaving the rest of the genome untouched. (newscientist.com)