We have already shown that this type of imaging detects abnormalities of the axon bundles before any reduction of retinal nerve fiber layer (RNFL) thickness (the most common clinical standard metric of axon integrity) can be detected. (brightfocus.org)
The secondary endpoint of change in thickness of the temporal quadrant and papillomacular bundle of the retinal nerve fiber layer from baseline to week 48 demonstrated a large statistically significant difference (p = 0.0359) between all GS010 - treated eyes and all sham - treated eyes, with untreated eyes showing a loss of 3.4 μm while treated eyes showed a limited loss of 0.6 μm. (gensight-biologics.com)
Use the GDx - Vcc diagnostic instrument to examine the thickness of the retinal nerve fiber layer as a step for the early detection of Glaucoma (jobhero.com)