At 9 weeks of age, R6 / 2 mice typically exhibit a modest deficit in acquisition of this task, and a more severe deficit in reversal learning. (psychogenics.com)
For the 5 - choice serial reaction time task (5 - CSRTT), delayed - match - to - position (DMTP) and cued reversal learning tasks, subjects had acquired the tasks prior to PCP exposure. (psychogenics.com)
Results: Subchronic PCP treatment induced deficits in episodic memory, cognitive flexibility and social functioning, assessed via the novel object recognition, cued reversal learning and social interaction tests. (psychogenics.com)