In contrast, variants in the MTHFR gene have been associated with increased risk of neural tube defects and cardiovascular disease; however, 60 - 70 % of individuals in the general population have one of the two most common MTHFR gene polymorphisms. (ashg.org)
The addition of folic acid to corn masa flour specifically targets Hispanic women since they have a higher risk of neural tube defects than non-Hispanic women, tend to have lower blood folate levels and consume fewer of the traditionally fortified foods. (sciencedaily.com)
While you may constantly hear about the importance of folic acid for the prevention of neural tube defects like spina bifida, research indicates that higher choline intake during pregnancy is associated with lower risk of neural tube defects as well. (pullingdownthemoon.com)