A key factor in this evaluation is the risk presented by the substance, which is a combined measure of hazards and routes of exposure for specific chemicals and materials. (treehugger.com)
But the intestine is also an important route of exposure to potentially harmful chemicals, and they can easily accumulate in tissue where they become toxic to their surroundings. (sciencedaily.com)
Multiple routes of exposure include ingestion and inhalation but most recently contact and skin exposure has been considered a major role in intensity of allergic symptoms. (blog.petmeds.com)