Heberlein: 80 - 90 % of Drosophila genes with ethanol - related phenotypes show same phenotypes in rodents #DROS2015 (genestogenomes.org)
All were discovered to have the same phenotype with the same mutation, which was located in the interferon - gamma (IFNGR) receptor, so the group began to explore what was causing this dysfunction. (sciencedaily.com)
For extended modules, many different combinations of perturbed genes could incapacitate the module, as a result of which mutations in different genes will appear to lead to the same phenotype (e.g., hypertrophic cardiomyopathy). (msb.embopress.org)