When those same transcription factors land on another part of the code, the risk of multiple sclerosis appears to rise. (sciencedaily.com)
The sequences of these enhancers were enriched for many of the same transcription factor (TF) binding motifs; the authors could propose upstream regulators for about half of the enhancer modules they observed. (massgenomics.org)
Next, the scientists created cardiac cells missing the same transcription factors to investigate how their interactions affect gene expression. (gladstone.org)