Three of the 17 patients who «lost» T790M demonstrated a new resistance mechanism on the second biopsy. (sciencedaily.com)
«As much as half of the time, the dominant resistance mechanisms observed on one biopsy may no longer be relevant on a second biopsy, and that second biopsy may uncover a new, potentially targetable, resistance mechanism,» said Dr. Piotrowska. (sciencedaily.com)