In nature, advantageous amino acid substitutions may be promoted by positive selection, but the general structural distributions of positively selected mutations and their effects on protein function remain poorly examined. (sciencedaily.com)
For most genes, only selected mutations are included. (omim.org)
Newly selected mutations in genes controlling sperm production show up in every ethnic group he and his team have studied; those genes may affect characteristics including abundance, motility, and viability. (discovermagazine.com)