Phrases with «sequence conservation»

"Sequence conservation" refers to the preservation of the same DNA or protein sequence across different species over long periods of time. It indicates that the genetic information or amino acid sequence is important for the proper functioning of an organism or for a specific biological function. Full definition

Sentences with «sequence conservation»

  • Such sequence conservation suggests that these areas are responsible for critical functions. (the-scientist.com)
  • Their importance is suggested by the predictions that each miRNA targets hundreds of genes and that the majority of protein - coding genes are miRNA targets; by their abundance, with some miRNAs expressed as high as 50,000 copies per cell; and by their sequence conservation, with some miRNAs conserved from sea urchins to humans. (hubrecht.eu)
  • The immunopurification (IP) of Argonaute (Ago), a central component of the RISC in the human and mouse, followed by microarray analyses (Ago IP / microarray method) makes it possible to isolate any Ago - associated miRNAs and mRNAs without relying on the mechanism of regulation (i.e. mRNA decay or translational suppression), or sequence conservation, enabling a comprehensive identification of the miRNA - target genes in an unbiased manner. (elifesciences.org)
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