Politics imposes serious burdens on not just the candidate but their families especially the spouse. (citifmonline.com)
Obesity and type 2 diabetes are not only serious burdens to afflicted individuals but are overwhelming our health care system and likely our economy as well. (scientificamerican.com)
A more serious burden plagued the British royal family until recently: hemophilia, a blood - clotting disorder. (discovermagazine.com)