The phrase "serious ramifications" means there will be important and significant consequences or outcomes as a result of certain actions or events. Full definition
Such a situation will have serious ramifications for students in the school setting. (teachermagazine.com.au)
During the course of their stories, players will have to make important choices which may have serious ramifications on what happens to certain characters. (mmobro.com)
Yes, this is a far reaching method of registration with serious ramifications. (dustanwoodhouse.ca)