The phrase "severe disruption" means a significant disturbance or interruption that has a strong and negative impact on a situation, activity, system, or routine. Full definition
A catastrophic injury or illness usually causes severe disruption to the central nervous system, which causes many other systems of the body to not operate properly. (koushanlaw.com)
Families experience severe disruption and many carers resign from fostering following an allegation. (fostertalk.org)
A catastrophic injury or illness very often causes severe disruption to the central nervous system, which in turn affects many other systems of the body. (personalinjuryattorney-1.com)