In exceptional circumstances, where an accommodation measure requires significant interference with the rights of other employees, and there are no other accommodation options available, accommodation may not be required. (ohrc.on.ca)
Children were assigned a diagnosis if either the parent or child reported that symptoms were causing significant interference in functioning, and if a Clinical Severity Rating (CSR) of 4 or more was assigned (in accordance with the clinician's manual of the ADIS - IV; Silverman and Albano 1996). (link.springer.com)
As long as the vaccine is being boostered instead of being given for the first time, corticosteroids do not cause significant interference with the production of an immune response to the vaccine. (vetinfo.com)