The phrase "single colony" refers to a group of living organisms, such as bacteria or animals, that originated from a single individual. Full definition
After careful analysis of over 80,000 ESTs to find full - length cDNA clones, including verification of the 3» ends of these clones, we have selected 5,849 non-redundant cDNA clones for single colony purification and re-arraying (see What is the Drosophila Gene Collection? (fruitfly.org)
Also, it is beneficial for continuous observation of the reprogramming process, in particular at single colony or even single cell levels. (journals.plos.org)
To isolate single colony variants in a non-mutating background, the floxed AID expression cassette was excised by culturing the cells in CM containing 20 nM 4 - hydroxitamoxifen (SIGMA) for three days followed by two rounds of cell sorting for stabilization. (journals.plos.org)