Repeated use of ibuprofen will increase the risk of toxicity even at doses that would not be toxic in single exposures. (vin.com)
He calls the Turner prize «in its heyday the biggest single exposure an artist could have on this planet». (theguardian.com)
What is unique about abortion is that a single exposure measurably increases breast cancer risk, presumably because maternal estradiol (estrogen) reaches such high levels during a normal pregnancy. (firstthings.com)