Death usually followed a single large dose. (clspress.com)
You might also want to split up your dosage and take half in the morning and half at night, if the single larger dose upsets your stomach. (healthyeating.sfgate.com)
It's also possible that creatine may directly improve power output through some other mechanism, as one study found that a single large dose of creatine improved neuromuscular function and increased power output within 24 hours, which is before it would have accumulated in muscle tissue. (legionathletics.com)