It activates specific signaling molecules, which leads to induction of genes that contribute to cell damage. (westonaprice.org)
Although therapies against specific signaling proteins or pathways have been remarkably successful at treating certain cancers, the tumors frequently develop resistance, leading to even more aggressive forms of the disease. (sciencemag.org)
They were also able to define specific signals which determine if this common ancestor cell will evolve into brown fat or skeletal muscle cell. (fitnessandpower.com)