Here, we elaborate on how these findings pertain to cancer cells dispersed in the tumor - adjacent stroma of breast cancer tissues, and how BH3 - mimetics may provide a therapeutic strategy to eliminate cancer cell populations that have passed through an EMT. (impactjournals.com)
In addition to defects in blood stem cells, MDS is also affected by the cells that surround the stem cells in the bone marrow, the so - called stroma cells. (ccri.uthscsa.edu)
Note how individual tumor cells (brown) or groups of tumor cells have become detached from the primary tumor (on the left) and are migrating into the surrounding normal tissue (the so - called stroma, blue staining). (sciencedaily.com)