They are planning strong replay protection, so you probably won't have to worry about replay attacks. (bitcointechtalk.com)
QuadrigaCX did sign the hard fork statement insisting on consensus and strong replay protection for hard forks, originally referring to the potential Bitcoin Unlimited hard fork. (bitcoinmagazine.com)
When asked by Bitcoin Magazine, the exchange further explained that it may or may not list the coins on the SegWit2x chain, which will in part depend on whether or not the SegWit2x chain implements strong replay protection. (bitcoinmagazine.com)