We are exploring the conformational properties of the tetraarylporphyrine core structure with different substituents of increasing size and molecular weight. (zib.de)
Despite being highly useful, multi-substituted benzene derivatives are rather difficult to synthesize due to the lack of selective methods to install different substituents at the desired positions. (sciencedaily.com)
Various synthetic approaches for the introduction of substituents on these indoles are available. (thno.org)