The phrase "such manipulation" refers to the act of controlling or influencing someone or something in a dishonest or unfair way. It means intentionally changing or directing things to achieve personal or biased objectives. Full definition
Within the data research community, we have known for years that such manipulation of data was possible through grand scale harvesting of social media data. (rte.ie)
Such manipulation of light — by transparency or contrast — has remained constant throughout the artist's work in all mediums. (artinamericamagazine.com)
The worms are capable of sucking out the sperm following copulation, but some worms have evolved filamentous structures on the sperm heads help protect against such manipulation by anchoring the sperm inside the antrum. (the-scientist.com)