In case you were wondering, depression shows up in mice as poorer performance on forced swim tests and less interest in sweets. (blog.addgene.org)
Researchers then gave the mice several behavioral tests for «depression» including the forced swim test, in which researchers measure how fast the mice give up swimming and decide to float. (sciencedaily.com)
Caldarone, B. J.; Wang, D.; Paterson, N. E.; Manzano, M.; Fedolak, A.; Cavino, K.; Kwan, M.; Hanania, T.; Chellappan, S. K.; Kozikowski, A. P.; Olivier, B.; Picciotto, M. R.; Ghavami, A. Dissociation between duration of action in the forced swim test in mice and nicotinic acetylcholine receptor occupancy with sazetidine, varenicline, and 5 - I - A85380. (psychogenics.com)