"Synapse loss" refers to the decrease or weakening of connections between nerve cells in the brain. It can hinder the normal transmission of information and impair brain function. Full definition
Our lab is working to identify how astrocytes interact with and regulate neuronal synapses throughout life: in development of neuronal circuits, in adult synaptic plasticity, and in synapse loss in aging. (salk.edu)
Remarkably, they found that anti-IFNAR did seem to have neuro - protective effects in mice with lupus, preventing synapse loss when compared with mice who were not given the drug. (sciencedaily.com)
In the first group extensive synapse loss occurred in the hippocampus — loss that did not occur in the mice in which C1q had been inhibited. (scientificamerican.com)