In some cases, the off - target effects of a drug could make it useful for treating conditions other than the one for which it was originally developed. (sciencedaily.com)
It might have unpredictable, off - target effects on the genome, and scientists don't know how to shut it down. (sciencemag.org)
The researchers can't be sure that the off - target effects actually caused the brain damage seen in the volunteers, however. (sciencemag.org)