All of the main characters in the film are driven by their love of music, and we also see how they turn away from music in times of despair. (dvdsleuth.com)
In other words, during times of despair, bonds are much more defensive. (financialsamurai.com)
There are also times of despair in which pet owners have to deal with the loss of a pet right there in an animal hospital or veterinary facility. (veterinarianedu.org)