The phrase "to destroy a relationship" means to cause serious damage or harm to a connection or bond between two or more people, often resulting in its complete breakdown or ruin. Full definition
It is called «parental alienation» and if ignored, it can (and probably will) completely destroy your relationship with your child. (movingpastdivorce.com)
Those disagreements may cause friction and some heated debates from time to time, but they won't destroy your relationship if you don't let them. (relevantmagazine.com)
They can further social interactions to help us build stronger connections in our communities, or allow us to destroy relationships by hiding behind a screen. (edutopia.org)