Having ASU in the Cosequin ASU formula is especially beneficial as NMX1000 ® avocado / soybean unsaponifiables, FCHG49 ® glucosamine hydrochloride and TRH122 ® low molecular weight chondroitin sulfate together were shown in cell studies to be more effective than the combination of glucosamine and chondroitin sulfate alone at inhibiting expression of several agents involved in the breakdown of cartilage. (cosequin.com)
Autophagy can be blocked in tumor cells and mouse models pharmacologically and genetically, the latter by inhibiting the expression of genes involved in the initiation of autophagy, for example BECN1 coding for the protein Beclin - 1. (sciencedaily.com)
Further, the combination of glucosamine and chondroitin sulfate plus ASU has been shown in cartilage cell studies to work better than the combination of glucosamine and chondroitin sulfate alone at inhibiting the expression of several agents involved in cartilage breakdown (click here for more information). (cosequinequine.com)