In a two - pronged attack, these viruses specifically target tumor cells while delivering a cargo of immune - boosting genes. (scientificamerican.com)
Hence, BH3 mimetics might represent an attractive approach of eliminating resistant subpopulations of cancer cells, thereby targeting both tumor cell invasion and cancer relapse. (impactjournals.com)
Because the toxin does not target the tumor cells themselves but rather the host - derived blood vessel cells, the strategy could be efficacious for a wide range of tumor types, the NIH team notes. (sciencedaily.com)