While this situation is bad for researchers, it turns out that the same sort of force may be helpful in cells by forcing the DNA open just a bit to get the ball rolling on transcribing a gene into messenger RNA (mRNA). (yeastgenome.org)
Prior studies from the Sancar lab showed that excision repair works more efficiently for actively transcribed genes in animals and bacteria. (sciencedaily.com)
α - Amanitin achieves its impressive deadliness by acting as a potent inhibitor of RNA polymerase II, the enzyme primarily responsible for transcribing genes into the messenger molecule RNA. (sciencedaily.com)