"Transcriptional enhancers" are specific sections of DNA that help increase the activity of nearby genes. They act like switches, turning genes on and off, and play an important role in controlling gene expression. Full definition
Leukemia - associated mutations drive cell growth by creating a powerful transcriptional enhancer upstream of an oncogene. (science.sciencemag.org)
For example, we discovered how the protein phosphatase calcineurin and its downstream effector protein NFAT act synergistically with the transcription factor MEF2 at transcriptional enhancer elements of selected genes, such as myoglobin, to medicate adaptive mechanisms by which skeletal myofibers acquire specialized contractile and metabolic properties in response to changing patterns of muscle contraction. (gladstone.org)
Berkeley Lab researchers played significant roles in earlier stages of the ENCODE project, helping to characterize transcriptional enhancers, which facilitate gene expression, by mapping enhancer - associated biochemical signatures in the genome and testing DNA sequences for enhancer activity. (newscenter.lbl.gov)