Highly Dynamic Transcriptional Signature of Distinct Macrophage Subsets during Sterile Inflammation, Resolution, and Tissue Repair (inmg.fr)
Then, through a survey of more than 1,100 drug candidates (all FDA - approved), they identified a short list of drugs likely to convert the abnormal transcriptional signature of a tumor to a more normal one. (sciencedaily.com)
The reprogrammed cells originally taken from schizophrenia patients showed the same transcriptional signatures (or underlying biology) as cells taken from postmortem patients, indicating that the stem cell - derived brain cells successfully recapitulated the disease and identifying possible biological variants that contribute to its onset. (nyscf.org)