The observation that HDL cholesterol did not increase in ApoC - III — treated mice would seem to support an LPL - independent mechanism as well, although the absence of cholesterol ester transfer protein in mice confounds this finding. (jci.org)
FFAT motifs are present in several other lipid transfer proteins leading Tim to propose that FFAT - motif proteins would act at contact sites by binding simultaneously to both the ER and another membrane. (peerj.com)
- Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolemia; Daniel J. Rader, MD, Perelman School of Medicine at the University of Pennsylvania. (clinicalresearchforum.org)