The former method necessitates however having crystals of the investigated protein, which in the case of transmembrane proteins has been extremely challenging. (sciencedaily.com)
The clustering of transmembrane receptors into defined nanoscale structures triggers and regulates specific signaling networks with unprecedented precision and is involved in transducing forces between the cell and the matrix. (regmednet.com)
Cystic fibrosis is a rare inherited disease caused by mutations in a single gene called cystic fibrosis transmembrane conductance regulator (CFTR) and affects 1 in every 2500 newborns in the UK and over 90000 people worldwide. (sciencedaily.com)