«Evaluation of the safety of long - term, daily oral administration of grapiprant, a novel drug for treatment of osteoarthritis pain and inflammation, in healthy dogs.» (elanco.com)
Only three of these treatments — physical therapy, NSAIDs, and the drug tramadol (short - term for severe pain)-- are recommended in the AAOS clinical practice guideline (CPG): «Non-arthroplasty Treatment of Osteoarthritis of the Knee.» (sciencedaily.com)
FDA Information — No claims can be made regarding CellRenew's direct effects on treatment of Osteoarthritis or other joint diseases. (appliedhealth.com)