As pro se litigants, we're at tremendous disadvantage against the opposing lawyers in our cases. (courtroom5.com)
Sugar promotes tremendous disadvantages and complications to human health. (cancertutor.com)
Mark S Kiselica writes in When Boys Become Parents, «For too long our culture has treated boys who become fathers... as detached misfits who are the architects of many of our nation's problems, rather than seeing these youth for who they really are: young men trying to navigate a complex array of difficult life circumstances that place them at a tremendous disadvantage.» (theguardian.com)