The phrase "triplet repeats" refers to a genetic condition where a specific sequence of three DNA building blocks repeats multiple times. This can cause problems in the functioning of genes and lead to certain diseases or disorders. Full definition
«We've known that in other triplet repeat expansion diseases, such as Huntington's disease, DNA repair enzymes are somehow involved in generating the expansion,» said Joel M. Gottesfeld, a professor at The Scripps Research Institute, and the study's senior author. (scripps.edu)
The suite of new findings provides a critical window on the mechanism for CJD and similar triplet repeat diseases like Huntington's. (sciencemag.org)
Fragile X occurs when a segment in the FMR1 gene on the X chromosome called the CGG triplet repeat is lengthened from the normal 5 to 40 repeats to 200 repeats in people with full mutation FXS. (sciencedaily.com)